产品货号：
GS4723
中文名称：
重组人HCC-1,66a.a./CCL14
英文名称：
Recombinant Human Hemofiltrate CC Chemokine-1, 66a.a./CCL14
产品规格：
2μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 7.8kDa,a single non-glycosylated polypeptide chain containing 66 amino acids.
储存条件：冷冻（-20℃）
概述
Human CCL14 is belonging to the CC chemokine family.It is encoded by the gene CCL14.CCL14 has two isoforms,CCL14a(HCC-1)and CCL14b(HCC-3).The sequence of HCC-3 differs from HCC-1 as follow:27-27 R→ QTGGKPKVVKIQLKLVG.CCL14 was first isolated from the hemofiltrate of human patients with chronic renal failure.The N-terminal processed forms HCC-1(3-74),HCC-1(4-74)and HCC-1(9-74)are produced in small amounts by proteolytic cleavage after secretion in blood.CCL14 promotes chemotaxis of T lymphocytes,monocytes and eosinophils,and inhibits infection of M-tropic human immunodeficiency virus type 1 and is a ligand for CCR1,CCR3 and CCR5.Recombinant human CCL14(66 a.a.)contains 66 amino acid residues and activation of the HCC 1/CCL14a precursor to active peptide is mediated by the urokinase type plasminogen activator or plasmin.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人HCC-1,66a.a./CCL14，HCC-1, 66a.a./CCL14, Human
储存条件：冷冻（-20℃）
概述
Human CCL14 is belonging to the CC chemokine family.It is encoded by the gene CCL14.CCL14 has two isoforms,CCL14a(HCC-1)and CCL14b(HCC-3).The sequence of HCC-3 differs from HCC-1 as follow:27-27 R→ QTGGKPKVVKIQLKLVG.CCL14 was first isolated from the hemofiltrate of human patients with chronic renal failure.The N-terminal processed forms HCC-1(3-74),HCC-1(4-74)and HCC-1(9-74)are produced in small amounts by proteolytic cleavage after secretion in blood.CCL14 promotes chemotaxis of T lymphocytes,monocytes and eosinophils,and inhibits infection of M-tropic human immunodeficiency virus type 1 and is a ligand for CCR1,CCR3 and CCR5.Recombinant human CCL14(66 a.a.)contains 66 amino acid residues and activation of the HCC 1/CCL14a precursor to active peptide is mediated by the urokinase type plasminogen activator or plasmin.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞95%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 5.0-20ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 2×PBS,pH 7.4,5%trehalose. |
| 内毒素 | Less than 1 EU/μg of rHuHCC-1,66a.a./CCL14 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | GPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN |
相关搜索：重组人HCC-1,66a.a./CCL14，HCC-1, 66a.a./CCL14, Human